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Concept information

Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins > Poly-ADP-Ribose Binding Proteins > Apoptosis Inducing Factor
Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Poly-ADP-Ribose Binding Proteins > Apoptosis Inducing Factor
Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Apoptosis Inducing Factor
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Apoptosis Inducing Factor
Enzymes and Coenzymes > Enzymes > Oxidoreductases > NADH, NADPH Oxidoreductases > Apoptosis Inducing Factor
Amino Acids, Peptides, and Proteins > Proteins > Flavoproteins > Apoptosis Inducing Factor

Terme préférentiel

Apoptosis Inducing Factor  

Type

  • mesh:Descriptor

Définition

  • A flavoprotein that functions as a powerful antioxidant in the MITOCHONDRIA and promotes APOPTOSIS when released from the mitochondria. In mammalian cells AIF is released in response to pro-apoptotic protein members of the bcl-2 protein family. It translocates to the CELL NUCLEUS and binds DNA to stimulate CASPASE-independent CHROMATIN condensation.

Concept générique

Synonyme(s)

  • AIF Apoptosis Regulatory Protein
  • Apoptosis-Inducing Factor
  • Mitochondrial Apoptosis-Inducing Factor

Qualificatif(s) autorisé(s)

Traductions

  • Facteur inducteur d'apoptose

    français

  • AIF (Apoptosis Inducing Factor)
  • Facteur AIF
  • Facteur inducteur de l'apoptose
  • Facteur mitochondrial inducteur d'apoptose
  • Facteurs mitochondriaux inducteurs d'apoptose
  • Protéine régulatrice d'apoptose AIF

URI

http://data.loterre.fr/ark:/67375/JVR-SB69MK6J-H

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RDF/XML TURTLE JSON-LD Date de création 30/06/2005, dernière modification le 24/05/2017