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Concept information

Biological Factors > Intercellular Signaling Peptides and Proteins > Angiogenic Proteins > Angiopoietin-like Proteins > Angiopoietin-Like Protein 4
... > Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > Angiogenic Proteins > Angiopoietin-like Proteins > Angiopoietin-Like Protein 4
... > Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > Angiogenic Proteins > Angiopoietin-like Proteins > Angiopoietin-Like Protein 4

Terme préférentiel

Angiopoietin-Like Protein 4  

Type

  • mesh:Descriptor

Définition

  • A secreted angiopoietin-like protein expressed under hypoxic conditions by ENDOTHELIAL CELLS. It inhibits cell proliferation, cell migration, and tubule formation; the inactive form accumulates in the endothelial EXTRACELLULAR MATRIX, reducing vascular leakage. ANGPTL4 has direct roles in regulating glucose and lipid metabolism, as well as INSULIN SENSITIVITY, and may also function as a regulator of angiogenesis and tumorigenesis.

Concept générique

Synonyme(s)

  • Angiopoietin-related Protein 4
  • ANGPTL4 Protein

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-SK5W2JCF-L

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RDF/XML TURTLE JSON-LD Date de création 11/07/2017, dernière modification le 27/06/2021