Concept information
Terme préférentiel
ADAM17 Protein
Type
-
mesh:Descriptor
Définition
- A disintegrin and metalloproteinase domain-containing protein that cleaves the membrane-bound precursor of TUMOR NECROSIS FACTOR-ALPHA to its mature form. It cleaves several other CELL SURFACE PROTEINS, including INTERLEUKIN-1 RECEPTOR TYPE II; TRANSFORMING GROWTH FACTOR ALPHA; L-SELECTIN; MUCIN-1; and AMYLOID BETA-PROTEIN PRECURSOR. It can also function as an activator of the Notch signaling pathway by mediating the cleavage of NOTCH RECEPTORS.
Concept générique
Synonyme(s)
- ADAM-17
- ADAM-17 Protein
- CD156b Antigen
- Disintegrin and Metalloproteinase Domain-Containing Protein 17
- TACA (Enzyme)
- TACE (Enzyme)
- TNF-alpha Convertase
- TNF-alpha Converting Enzyme
- Tumor Necrosis Factor Alpha Convertase
- Tumor Necrosis Factor-alpha Convertase
- Tumor Necrosis Factor-alpha Converting Enzyme
Qualificatif(s) autorisé(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
Traductions
-
français
-
ADAM-17
-
Antigène CD156b
-
CD156b
-
Convertase du facteur de nécrose tumorale alpha
-
Convertase du TNF-alpha
-
Enzyme de conversion du facteur de nécrose tumorale alpha
-
Enzyme de conversion du TNF-alpha
-
Protéine ADAM-17
-
Protéine-17 contenant des domaines désintégrine et métalloprotéinase
-
Protéine-17 contenant un domaine désintégrine et un domaine métalloprotéinase
-
TACA (Enzyme)
-
TACE (Enzyme)
URI
http://data.loterre.fr/ark:/67375/JVR-SL3M8DFH-L
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