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Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > WNK Lysine-Deficient Protein Kinase 1
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > WNK Lysine-Deficient Protein Kinase 1
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein Serine-Threonine Kinases > WNK Lysine-Deficient Protein Kinase 1
... > Biological Factors > Antigens > Antigens, Surface > Histocompatibility Antigens > Minor Histocompatibility Antigens > WNK Lysine-Deficient Protein Kinase 1
... > Biological Factors > Antigens > Isoantigens > Histocompatibility Antigens > Minor Histocompatibility Antigens > WNK Lysine-Deficient Protein Kinase 1

Terme préférentiel

WNK Lysine-Deficient Protein Kinase 1  

Type

  • mesh:Descriptor

Définition

  • A serine-threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. It functions as an activator and inhibitor of sodium-coupled chloride co-transporters and as an inhibitor of potassium-coupled chloride co-transporters. Mutations in the WNK1 gene are associated with type 2C PSEUDOHYPOALDOSTERONISM and type 2A HEREDITARY SENSORY AND AUTONOMIC NEUROPATHIES.

Concept générique

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URI

http://data.loterre.fr/ark:/67375/JVR-T389ZQ0Z-0

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RDF/XML TURTLE JSON-LD Date de création 11/07/2017, dernière modification le 28/06/2021