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Concept information

Genetic Phenomena > Genetic Variation > Mutation > Codon, Nonsense
... > Genetic Phenomena > Genetic Structures > Genetic Code > Codon > Codon, Terminator > Codon, Nonsense
... > Genetic Phenomena > Genetic Structures > Genome > Genome Components > Genes > Gene Components > Codon > Codon, Terminator > Codon, Nonsense
... > Nucleic Acids, Nucleotides, and Nucleosides > Nucleic Acids > RNA > RNA, Messenger > Codon > Codon, Terminator > Codon, Nonsense

Terme préférentiel

Codon, Nonsense  

Type

  • mesh:Descriptor

Définition

  • An amino acid-specifying codon that has been converted to a stop codon (CODON, TERMINATOR) by mutation. Its occurance is abnormal causing premature termination of protein translation and results in production of truncated and non-functional proteins. A nonsense mutation is one that converts an amino acid-specific codon to a stop codon. A mutation that converts a sense codon (CODON) into a stop codon (CODON, TERMINATOR) or an unassigned codon and leads to the formation of truncated proteins. A codon that is not assigned to an amino acid and is not a stop codon (CODON, TERMINATOR). Although they may lead to premature termination of translation, unassigned codons do not bind translation release factors (PEPTIDE TERMINATION FACTORS), as do stop codons.

Concept générique

Synonyme(s)

  • Codon, Termination, Premature
  • Nonsense Codon
  • Premature Stop Codon
  • Premature Termination Codon

Qualificatif(s) autorisé(s)

Traductions

  • Codon non-sens

    français

  • Codon de terminaison prématuré
  • Codon stop prématuré

URI

http://data.loterre.fr/ark:/67375/JVR-T739CM7H-2

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RDF/XML TURTLE JSON-LD Date de création 03/06/1994, dernière modification le 09/07/2013