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Concept information

Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > Homer Scaffolding Proteins
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > Homer Scaffolding Proteins
Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Adaptor Proteins, Signal Transducing > Homer Scaffolding Proteins

Terme préférentiel

Homer Scaffolding Proteins  

Type

  • mesh:Descriptor

Définition

  • Homer proteins belong to a family of adaptor and scaffold proteins which include Homer1, Homer2 and Homer3. Homer1 and Homer2 play a role in the regulation of calcium homeostasis, whereas Homer3 functions in stimulating changes in actin dynamics in neurons and T-cells. Homer proteins are best known as scaffold proteins at the post-synaptic density where they facilitate synaptic signaling. They function as a molecular switch in metabotropic glutamate receptor (MGluR) signaling, and are associated with human Fragile X syndrome.

Concept générique

Synonyme(s)

  • Homer Protein
  • Homer Proteins

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-TL3GQPF5-F

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RDF/XML TURTLE JSON-LD Date de création 11/07/2016, dernière modification le 30/06/2021