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Concept information

Terme préférentiel

Cyclic Nucleotide Phosphodiesterases, Type 2  

Type

  • mesh:Descriptor

Définition

  • A cyclic nucleotide phosphodiesterase subfamily that is activated by the binding of CYCLIC GMP to an allosteric domain found on the enzyme. Multiple enzyme variants of this subtype can be produced due to multiple alternative mRNA splicing. The subfamily is expressed in a broad variety of tissues and may play a role in mediating cross-talk between CYCLIC GMP and CYCLIC CMP pathways. Although the type 2 enzymes are classified as 3',5'-cyclic-AMP phosphodiesterases (EC 3.1.4.17), members of this class have additional specificity for CYCLIC GMP.

Synonyme(s)

  • Cyclic GMP-Stimulated Phosphodiesterase
  • Cyclic Nucleotide Phosphodiesterase PDE2 Family
  • PDE2 Phosphodiesterase
  • PDE2 Phosphodiesterases

Traductions

  • français

  • PDE de type 2 stimulée par la GMPc
  • PDE-2 stimulée par la GMPc
  • Phosphodiestérase stimulée par GMPc
  • Phosphodiestérase stimulée par la GMP cyclique
  • Phosphodiestérase stimulée par le nucléotide cyclique GMPc
  • Phosphodiestérases des nucléotides cycliques de type 2
  • Phosphodiestérases des nucléotides cycliques de type II
  • Phosphodiestérases PDE2

URI

http://data.loterre.fr/ark:/67375/JVR-TP1SV5ZW-T

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RDF/XML TURTLE JSON-LD Date de création 09/07/2007, dernière modification le 21/05/2021