Concept information
Amino Acids, Peptides, and Proteins
Peptides
Intercellular Signaling Peptides and Proteins
Cytokines
Amino Acids, Peptides, and Proteins
Proteins
Intercellular Signaling Peptides and Proteins
Cytokines
Terme préférentiel
Transforming Growth Factor beta
Type
-
mesh:Descriptor
Définition
- A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins.
Concept générique
Concepts spécifiques
Synonyme(s)
- Bone-Derived Transforming Growth Factor
- Milk Growth Factor
- Platelet Transforming Growth Factor
- TGF-beta
- TGFbeta
Qualificatif(s) autorisé(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Traductions
-
français
-
Facteur de croissance de transformation bêta
-
Facteur de croissance du lait
-
Facteur de croissance TGF bêta
-
Facteur de croissance transformant des plaquettes
-
Facteur de croissance transformant plaquettaire
-
Facteur transformant TGF b
-
Facteur transformant TGF bêta
-
Facteurs de croissance transformants bêta
-
TGF-b
-
TGF-bêta
-
TGFbêta
URI
http://data.loterre.fr/ark:/67375/JVR-V0H2ZLDC-S
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}