Concept information
Terme préférentiel
Mitotane
Type
-
mesh:Descriptor
Définition
- A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
Concept générique
Synonyme(s)
- 53-19-0 (Mitotane)
- 78E4J5IB5J
- Benzene, 1-chloro-2-(2,2-dichloro-1-(4-chlorophenyl)ethyl)-
- Mytotan
- o,p-DDD
- ortho,para-DDD
Qualificatif(s) autorisé(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Action(s) pharmacologique(s)
Traductions
-
français
-
53-19-0 (Mitotane)
-
78E4J5IB5J
-
Benzene, 1-chloro-2-(2,2-dichloro-1-(4-chlorophenyl)ethyl)-
URI
http://data.loterre.fr/ark:/67375/JVR-V1FZ9FBN-V
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