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Concept information

... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Platelet Membrane Glycoproteins > Integrin alphaVbeta3
... > Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > Membrane Glycoproteins > Platelet Membrane Glycoproteins > Integrin alphaVbeta3
... > Carbohydrates > Glycoconjugates > Glycoproteins > Membrane Glycoproteins > Platelet Membrane Glycoproteins > Integrin alphaVbeta3
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Glycoproteins > Platelet Membrane Glycoproteins > Integrin alphaVbeta3
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Integrins > Receptors, Cytoadhesin > Receptors, Vitronectin > Integrin alphaVbeta3

Terme préférentiel

Integrin alphaVbeta3  

Type

  • mesh:Descriptor

Définition

  • An integrin that binds to a variety of plasma and extracellular matrix proteins containing the conserved RGD amino acid sequence and modulates cell adhesion. Integrin alphavbeta3 is highly expressed in OSTEOCLASTS where it may play role in BONE RESORPTION. It is also abundant in vascular smooth muscle and endothelial cells, and in some tumor cells, where it is involved in angiogenesis and cell migration. Although often referred to as the vitronectin receptor there is more than one receptor for vitronectin (RECEPTORS, VITRONECTIN).

Concept générique

Concepts associés

Synonyme(s)

  • alpha-v beta-3 Integrin Receptors
  • Integrin alpha-v beta-3
  • Receptors, alpha-v beta-3 Integrin
  • Vitronectin Receptor

Qualificatif(s) autorisé(s)

Traductions

  • Intégrine alphaVbêta3

    français

  • Intégrine alpha-V-bêta-3
  • Intégrine alphaV bêta3
  • Récepteur de la vitronectine

URI

http://data.loterre.fr/ark:/67375/JVR-V7W6RV9F-F

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RDF/XML TURTLE JSON-LD Date de création 02/07/2002, dernière modification le 09/07/2013