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Concept information

Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Kruppel-Like Transcription Factors > Promyelocytic Leukemia Zinc Finger Protein
Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Kruppel-Like Transcription Factors > Promyelocytic Leukemia Zinc Finger Protein

Terme préférentiel

Promyelocytic Leukemia Zinc Finger Protein  

Type

  • mesh:Descriptor

Définition

  • A Kruppel-type transcription factor consisting of an N-terminal BTB DOMAIN and nine CYS2-HIS2 ZINC FINGERS. It localizes to the nucleus and regulates cell cycle progression and gene expression for tissue development and homeostasis; it may also function as an epigenetic regulator through its interactions with HISTONE DEACETYLASE. Genetic rearrangements involving the ZBTB16 gene are associated with ACUTE PROMYELOCYTIC LEUKEMIA.

Concept générique

Synonyme(s)

  • PLZF Protein
  • Promyelocytic Leukaemia Zinc Finger Protein
  • ZBTB16 Protein
  • Zinc Finger and BTB Domain Containing 16 Protein

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-VKZ967WZ-J

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RDF/XML TURTLE JSON-LD Date de création 11/07/2017, dernière modification le 21/05/2018