Concept information
Amino Acids, Peptides, and Proteins
Proteins
DNA-Binding Proteins
Basic Helix-Loop-Helix Transcription Factors
Amino Acids, Peptides, and Proteins
Proteins
Transcription Factors
Basic Helix-Loop-Helix Transcription Factors
Amino Acids, Peptides, and Proteins
Peptides
Intracellular Signaling Peptides and Proteins
Circadian Rhythm Signaling Peptides and Proteins
Terme préférentiel
CLOCK Proteins
Type
-
mesh:Descriptor
Définition
- Basic helix-loop-helix (bHLH) domain-containing proteins that contain intrinsic HISTONE ACETYLTRANSFERASE activity and play important roles in CIRCADIAN RHYTHM regulation. Clock proteins combine with Arntl proteins to form heterodimeric transcription factors that are specific for E-BOX ELEMENTS and stimulate the transcription of several E-box genes that are involved in cyclical regulation. This transcriptional activation also sets into motion a time-dependent feedback loop which in turn down-regulates the expression of clock proteins.
Concept générique
Synonyme(s)
- Circadian Locomotor Output Cycles Kaput Proteins
- CLOCK Protein
Qualificatif(s) autorisé(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
Traductions
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français
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Circadian Locomoter Output Cycles Kaput Proteins
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Protéines horloges
URI
http://data.loterre.fr/ark:/67375/JVR-VS3LDFW6-N
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