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Concept information

Terme préférentiel

CLOCK Proteins  

Type

  • mesh:Descriptor

Définition

  • Basic helix-loop-helix (bHLH) domain-containing proteins that contain intrinsic HISTONE ACETYLTRANSFERASE activity and play important roles in CIRCADIAN RHYTHM regulation. Clock proteins combine with Arntl proteins to form heterodimeric transcription factors that are specific for E-BOX ELEMENTS and stimulate the transcription of several E-box genes that are involved in cyclical regulation. This transcriptional activation also sets into motion a time-dependent feedback loop which in turn down-regulates the expression of clock proteins.

Synonyme(s)

  • Circadian Locomotor Output Cycles Kaput Proteins
  • CLOCK Protein

Traductions

  • français

  • Circadian Locomoter Output Cycles Kaput Proteins
  • Protéines horloges

URI

http://data.loterre.fr/ark:/67375/JVR-VS3LDFW6-N

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RDF/XML TURTLE JSON-LD Date de création 06/07/2009, dernière modification le 30/06/2018