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Concept information

... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Serum Globulins > Immunoglobulins > Immunoglobulin Fragments > Immunoglobulin Fc Fragments
... > Amino Acids, Peptides, and Proteins > Proteins > Globulins > Serum Globulins > Immunoglobulins > Immunoglobulin Fragments > Immunoglobulin Fc Fragments
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Immunoproteins > Immunoglobulins > Immunoglobulin Fragments > Immunoglobulin Fc Fragments
Amino Acids, Peptides, and Proteins > Peptides > Peptide Fragments > Immunoglobulin Fragments > Immunoglobulin Fc Fragments
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Serum Globulins > Immunoglobulins > Immunoglobulin Constant Regions > Immunoglobulin Fc Fragments
... > Amino Acids, Peptides, and Proteins > Proteins > Globulins > Serum Globulins > Immunoglobulins > Immunoglobulin Constant Regions > Immunoglobulin Fc Fragments
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Immunoproteins > Immunoglobulins > Immunoglobulin Constant Regions > Immunoglobulin Fc Fragments

Terme préférentiel

Immunoglobulin Fc Fragments  

Type

  • mesh:Descriptor

Définition

  • Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.

Concept générique

Concepts spécifiques

Concepts associés

Synonyme(s)

  • Fc Fragment
  • Fc Fragments
  • Fc Immunoglobulin
  • Fc Immunoglobulins
  • Ig Fc Fragments
  • Immunoglobulin Fc Fragment
  • Immunoglobulins, Fc
  • Immunoglobulins, Fc Fragment

Qualificatif(s) autorisé(s)

Action(s) pharmacologique(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-W48M2QVD-H

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RDF/XML TURTLE JSON-LD Date de création 01/01/1999, dernière modification le 30/06/2021