Concept information
Terme préférentiel
Multiple Endocrine Neoplasia Type 2a
Type
-
mesh:Descriptor
Définition
- A form of multiple endocrine neoplasia characterized by the presence of medullary carcinoma (CARCINOMA, MEDULLARY) of the THYROID GLAND, and usually with the co-occurrence of PHEOCHROMOCYTOMA, producing CALCITONIN and ADRENALINE, respectively. Less frequently, it can occur with hyperplasia or adenoma of the PARATHYROID GLANDS. This disease is due to gain-of-function mutations of the MEN2 gene on CHROMOSOME 10 (Locus: 10q11.2), also known as the RET proto-oncogene that encodes a RECEPTOR PROTEIN-TYROSINE KINASE. It is an autosomal dominant inherited disease.
Concept générique
Synonyme(s)
- MEA 2a
- MEA II
- MEA IIa
- MEN 2
- MEN 2a
- MEN2a
- MEN-2A Syndrome
- MEN II
- MEN IIa
- Multiple Endocrine Neoplasia Type 2
- Multiple Endocrine Neoplasia, Type IIa
- Multiple Endocrine Neoplasms Type 2a
- Neoplasia, Multiple Endocrine Type 2a
- Neoplasms, Multiple Endocrine Type 2a
- Pheochromocytoma And Amyloid-Producing Medullary Thyroid Carcinoma
- Sipple Syndrome
Qualificatif(s) autorisé(s)
- blood (Qualifier)
- blood supply (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemically induced (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- complications (Qualifier)
- congenital (Qualifier)
- diagnosis (Qualifier)
- diagnostic imaging (Qualifier)
- diet therapy (Qualifier)
- drug therapy (Qualifier)
- economics (Qualifier)
- embryology (Qualifier)
- enzymology (Qualifier)
- epidemiology (Qualifier)
- ethnology (Qualifier)
- etiology (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- metabolism (Qualifier)
- microbiology (Qualifier)
- mortality (Qualifier)
- nursing (Qualifier)
- parasitology (Qualifier)
- pathology (Qualifier)
- physiopathology (Qualifier)
- prevention & control (Qualifier)
- psychology (Qualifier)
- radiotherapy (Qualifier)
- rehabilitation (Qualifier)
- secondary (Qualifier)
- surgery (Qualifier)
- therapy (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
- veterinary (Qualifier)
- virology (Qualifier)
Traductions
-
français
-
Adénomatose endocrinienne multiple de type 2a
-
Apudomatose de type IIa
-
NEM 2a
-
NEM IIa
-
NEM2a
-
Polyadénomatose endocrinienne de type 2A
-
Syndrome de Sipple
URI
http://data.loterre.fr/ark:/67375/JVR-WS3K33VK-R
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