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Concept information

Terme préférentiel

Immunoglobulin Variable Region  

Type

  • mesh:Descriptor

Définition

  • That region of the immunoglobulin molecule that varies in its amino acid sequence and composition, and comprises the binding site for a specific antigen. It is located at the N-terminus of the Fab fragment of the immunoglobulin. It includes hypervariable regions (COMPLEMENTARITY DETERMINING REGIONS) and framework regions. The paired immunoglobulin fragments composed of the variable domains of the heavy and light chains.

Synonyme(s)

  • Ig Variable Region
  • Immunoglobulin V
  • Variable Region, Ig
  • Variable Region, Immunoglobulin

Action(s) pharmacologique(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-WX56JBDJ-S

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RDF/XML TURTLE JSON-LD Date de création 16/04/1976, dernière modification le 20/11/2015