Concept information
Terme préférentiel
Integrin alpha Chains
Type
-
mesh:Descriptor
Définition
- The alpha subunits of integrin heterodimers (INTEGRINS), which mediate ligand specificity. There are approximately 18 different alpha chains, exhibiting great sequence diversity; several chains are also spliced into alternative isoforms. They possess a long extracellular portion (1200 amino acids) containing a MIDAS (metal ion-dependent adhesion site) motif, and seven 60-amino acid tandem repeats, the last 4 of which form EF HAND MOTIFS. The intracellular portion is short with the exception of INTEGRIN ALPHA4.
Concept générique
Concepts spécifiques
Synonyme(s)
- alpha Integrins
- Integrin alpha Subunits
Qualificatif(s) autorisé(s)
- administration & dosage (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- physiology (Qualifier)
- radiation effects (Qualifier)
- therapeutic use (Qualifier)
- ultrastructure (Qualifier)
Traductions
-
français
-
Chaines alpha des intégrines
-
Chaînes alpha des intégrines
-
Sous-unités alpha des intégrines
URI
http://data.loterre.fr/ark:/67375/JVR-X5X803P5-Z
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