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Concept information

Inorganic Chemicals > Coordination Complexes > Oxaliplatin
Organic Chemicals > Coordination Complexes > Oxaliplatin

Terme préférentiel

Oxaliplatin  

Type

  • mesh:Descriptor

Définition

  • An organoplatinum complex in which the platinum atom is complexed with 1,2-diaminocyclohexane, and with an oxalate ligand which is displaced to yield active oxaliplatin derivatives. These derivatives form inter- and intra-strand DNA crosslinks that inhibit DNA replication and transcription. Oxaliplatin is an antineoplastic agent that is often administered with FLUOROURACIL and FOLINIC ACID in the treatment of metastatic COLORECTAL NEOPLASMS.

Concept générique

Synonyme(s)

  • 04ZR38536J
  • 1,2-Diaminocyclohexane Platinum Oxalate
  • 1,2-Diamminocyclohexane(trans-1)oxolatoplatinum(II)
  • 61758-77-8 ((SP-4-2-(1S-trans))-isomer)
  • 61913-68-6 ((SP-4-3-(cis))-isomer)
  • L-OHP Cpd
  • Oxalato-(1,2-cyclohexanediamine)platinum II
  • Oxaliplatine
  • Oxaliplatin, (SP-4-2-(1R-trans))-isomer
  • Platinum(2+) ethanedioate (1R,2R)-1,2-cyclohexanediamine (1:1:1)
  • Platinum(II)-1,2-cyclohexanediamine Oxalate

Qualificatif(s) autorisé(s)

Action(s) pharmacologique(s)

Traductions

  • Oxaliplatine

    français

  • 04ZR38536J
  • 61758-77-8 ((SP-4-2-(1S-trans))-isomer)
  • 61913-68-6 ((SP-4-3-(cis))-isomer)

URI

http://data.loterre.fr/ark:/67375/JVR-XKTP00R8-V

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RDF/XML TURTLE JSON-LD Date de création 09/07/2018, dernière modification le 05/07/2019