Passer au contenu principal

Medical Subject Headings (thesaurus)

Choisissez le vocabulaire dans lequel chercher

aligner
annoter
télécharger

Concept information

Immune System Phenomena > Immunogenetic Phenomena > Gene Rearrangement, B-Lymphocyte > Gene Rearrangement, B-Lymphocyte, Heavy Chain > Immunoglobulin Class Switching
Genetic Phenomena > Gene Rearrangement > Gene Rearrangement, B-Lymphocyte > Gene Rearrangement, B-Lymphocyte, Heavy Chain > Immunoglobulin Class Switching

Terme préférentiel

Immunoglobulin Class Switching  

Type

  • mesh:Descriptor

Définition

  • Gene rearrangement of the B-lymphocyte which results in a substitution in the type of heavy-chain constant region that is expressed. This allows the effector response to change while the antigen binding specificity (variable region) remains the same. The majority of class switching occurs by a DNA recombination event but it also can take place at the level of RNA processing.

Concept générique

Concepts associés

Synonyme(s)

  • Class Switching
  • Ig Class Switching
  • Isotype Switching

Qualificatif(s) autorisé(s)

Traductions

  • Commutation de classe des immunoglobulines

    français

  • Commutation d'isotype
  • Commutation de classe
  • Commutation de classe des Ig
  • Commutation isotypique
  • Commutation isotypique des Ig
  • Commutation isotypique des immunoglobulines
  • Switch isotypique

URI

http://data.loterre.fr/ark:/67375/JVR-XKXHNXDL-D

Télécharger ce concept :

RDF/XML TURTLE JSON-LD Date de création 17/06/1993, dernière modification le 05/07/2019