Concept information
Terme préférentiel
Podophyllotoxin
Type
-
mesh:Descriptor
Définition
- A lignan (LIGNANS) found in PODOPHYLLIN resin from the roots of PODOPHYLLUM plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives.
Concept générique
Concepts spécifiques
Synonyme(s)
- 4375-06-8 ((5R-(5 alpha,5a alpha,8a alpha,9 beta))-isomer)
- 4375-07-9 ((5R-(5 alpha,5a beta,8a alpha,9 beta))-isomer)
- 477-47-4 ((5R-(5 alpha,5a alpha,8a alpha,9 alpha))-isomer)
- 518-28-5 (Podophyllotoxin)
- 55568-79-1 ((5R-(5 alpha,5a alpha,8a beta,9 alpha))-isomer)
- Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, (5R-(5alpha,5abeta,8aalpha,9alpha))-
- L36H50F353
- Podofilox
Qualificatif(s) autorisé(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Action(s) pharmacologique(s)
Traductions
-
français
-
4375-06-8 ((5R-(5 alpha,5a alpha,8a alpha,9 beta))-isomer)
-
4375-07-9 ((5R-(5 alpha,5a beta,8a alpha,9 beta))-isomer)
-
477-47-4 ((5R-(5 alpha,5a alpha,8a alpha,9 alpha))-isomer)
-
518-28-5 (Podophyllotoxin)
-
55568-79-1 ((5R-(5 alpha,5a alpha,8a beta,9 alpha))-isomer)
-
Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, (5R-(5alpha,5abeta,8aalpha,9alpha))-
-
L36H50F353
URI
http://data.loterre.fr/ark:/67375/JVR-XNGT3QH2-X
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