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Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Acute-Phase Proteins > Trypsin Inhibitor, Kazal Pancreatic
... > Chemical Actions and Uses > Pharmacologic Actions > Molecular Mechanisms of Pharmacological Action > Enzyme Inhibitors > Protease Inhibitors > Serine Proteinase Inhibitors > Serine Peptidase Inhibitors, Kazal Type > Trypsin Inhibitor, Kazal Pancreatic
Amino Acids, Peptides, and Proteins > Peptides > Proteinase Inhibitory Proteins, Secretory > Serine Peptidase Inhibitors, Kazal Type > Trypsin Inhibitor, Kazal Pancreatic
Amino Acids, Peptides, and Proteins > Proteins > Proteinase Inhibitory Proteins, Secretory > Serine Peptidase Inhibitors, Kazal Type > Trypsin Inhibitor, Kazal Pancreatic

Terme préférentiel

Trypsin Inhibitor, Kazal Pancreatic  

Type

  • mesh:Descriptor

Définition

  • A secreted KAZAL MOTIF-containing serine peptidase inhibitor that inhibits TRYPSIN. It is a protein composed of 56 amino acid residues and is different in amino acid composition and physiological activity from the Kunitz bovine pancreatic trypsin inhibitor (APROTININ). It protects against the trypsin-mediated premature activation of ENZYME PRECURSORS in the PANCREAS. Mutations in the SPINK1 gene are associated with CHRONIC PANCREATITIS.

Concept générique

Concepts associés

Synonyme(s)

  • 50936-63-5
  • Acidic Pancreatic Trypsin Inhibitor
  • Inhibitor, Tumor-Associated Trypsin
  • Kazal Pancreatic Trypsin Inhibitor
  • Pancreatic Secretory Trypsin Inhibitor
  • Pancreatic Secretory Trypsin Inhibitor, Kazal
  • Pancreatic Trypsin Secretory Inhibitor, Kazal
  • Serine Peptidase Inhibitor, Kazal-Type 1
  • Serine Protease Inhibitor Kazal-Type 1
  • SPINK1
  • Trypsin Inhibitor Kazal Pancreatic
  • Trypsin Inhibitor, Pancreatic Secretory
  • Trypsin Inhibitor, Tumor-Associated
  • Tumor-Associated Trypsin Inhibitor

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-XSWDDRXZ-P

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RDF/XML TURTLE JSON-LD Date de création 19/11/1974, dernière modification le 29/04/2019