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Concept information

Nervous System Diseases > Neurodegenerative Diseases > Motor Neuron Disease
Nervous System Diseases > Neuromuscular Diseases > Motor Neuron Disease

Terme préférentiel

Motor Neuron Disease  

Type

  • mesh:Descriptor

Définition

  • Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)

Concept générique

Concepts spécifiques

Concepts associés

Synonyme(s)

  • Motor System Disease

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-Z2GQ3B9W-7

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RDF/XML TURTLE JSON-LD Date de création 21/06/1991, dernière modification le 25/06/2010