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Concept information

Organic Chemicals > Amides > Urea > Nitrosourea Compounds > Nimustine
Organic Chemicals > Nitroso Compounds > Nitrosourea Compounds > Nimustine

Terme préférentiel

Nimustine  

Type

  • mesh:Descriptor

Définition

  • Antineoplastic agent especially effective against malignant brain tumors. The resistance which brain tumor cells acquire to the initial effectiveness of this drug can be partially overcome by the simultaneous use of membrane-modifying agents such as reserpine, calcium antagonists such as nicardipine or verapamil, or the calmodulin inhibitor, trifluoperazine. The drug has also been used in combination with other antineoplastic agents or with radiotherapy for the treatment of various neoplasms.

Concept générique

Synonyme(s)

  • 0S726V972K
  • 42471-28-3 (Nimustine)
  • ACNU
  • Urea, N'-((4-amino-2-methyl-5-pyrimidinyl)methyl)-N-(2-chloroethyl)-N-nitroso-

Qualificatif(s) autorisé(s)

Action(s) pharmacologique(s)

Traductions

  • Nimustine

    français

  • 0S726V972K
  • 42471-28-3 (Nimustine)
  • Urea, N'-((4-amino-2-methyl-5-pyrimidinyl)methyl)-N-(2-chloroethyl)-N-nitroso-

URI

http://data.loterre.fr/ark:/67375/JVR-ZCSNV91X-L

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RDF/XML TURTLE JSON-LD Date de création 03/06/1988, dernière modification le 27/05/2020