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Concept information

Terme préférentiel

Neuroaxonal Dystrophies  

Type

  • mesh:Descriptor

Définition

  • A nonspecific term referring both to the pathologic finding of swelling of distal portions of axons in the brain and to disorders which feature this finding. Neuroaxonal dystrophy is seen in various genetic diseases, vitamin deficiencies, and aging. Infantile neuroaxonal dystrophy is an autosomal recessive disease characterized by arrested psychomotor development at 6 months to 2 years of age, ataxia, brain stem dysfunction, and quadriparesis. Juvenile and adult forms also occur. Pathologic findings include brain atrophy and widespread accumulation of axonal spheroids throughout the neuroaxis, peripheral nerves, and dental pulp. (From Davis & Robertson, Textbook of Neuropathology, 2nd ed, p927)

Concept générique

Synonyme(s)

  • NBIA2A

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-ZJP4M38Q-5

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RDF/XML TURTLE JSON-LD Date de création 10/06/1996, dernière modification le 08/07/2013