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Concept information

Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > eIF-2 Kinase
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > eIF-2 Kinase
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein Serine-Threonine Kinases > eIF-2 Kinase

Terme préférentiel

eIF-2 Kinase  

Type

  • mesh:Descriptor

Définition

  • A dsRNA-activated cAMP-independent protein serine/threonine kinase that is induced by interferon. In the presence of dsRNA and ATP, the kinase autophosphorylates on several serine and threonine residues. The phosphorylated enzyme catalyzes the phosphorylation of the alpha subunit of EUKARYOTIC INITIATION FACTOR-2, leading to the inhibition of protein synthesis.

Concept générique

Synonyme(s)

  • DAI Protein Kinase
  • Double Stranded RNA-Dependent eIF-2 alpha Protein Kinase
  • Double Stranded RNA-Dependent Kinase (dsl)
  • dsRNA-Activated Inhibitor
  • DSRNA-Dep Protein Kinase
  • eIF-2alpha Kinase
  • eRF, eIF-2 Recycling Factor
  • Eukaryotic Initiation Factor 2alpha Kinase
  • Heme-Controlled Inhibitor
  • Heme Controlled Repressor
  • Heme-Controlled Translational Repressor
  • Heme-Regulated eIF-2alpha Kinase
  • Hemin Controlled Repressor
  • Hemin-Controlled Translational Repressor
  • p65 Kinase
  • p68 Kinase
  • P68 Protein Kinase
  • Protein Kinase PKR
  • Protein Kinase, RNA Activated
  • RNA-Dependent Protein Kinase
  • Self-Phosphorylating Protein Kinase
  • TIK Kinase

Qualificatif(s) autorisé(s)

Traductions

  • eIF-2 Kinase

    français

  • p68 kinase
  • Protéine kinase ARN-dépendante
  • Protéine kinase PKR
  • Protéine-kinase activée
  • Protéine-kinase ARN-dépendante
  • Protéine-kinase PKR

URI

http://data.loterre.fr/ark:/67375/JVR-ZNMTQFS4-G

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RDF/XML TURTLE JSON-LD Date de création 02/07/1997, dernière modification le 21/05/2021