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Concept information

... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Immunoproteins > Complement System Proteins > Complement C5 > Complement C5a
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Immunoproteins > Complement System Proteins > Anaphylatoxins > Complement C5a

Terme préférentiel

Complement C5a  

Type

  • mesh:Descriptor

Définition

  • The minor fragment formed when C5 convertase cleaves C5 into C5a and COMPLEMENT C5B. C5a is a 74-amino-acid glycopeptide with a carboxy-terminal ARGININE that is crucial for its spasmogenic activity. Of all the complement-derived anaphylatoxins, C5a is the most potent in mediating immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE), smooth MUSCLE CONTRACTION; HISTAMINE RELEASE; and migration of LEUKOCYTES to site of INFLAMMATION.

Concept générique

Concepts spécifiques

Synonyme(s)

  • 80295-54-1
  • C5a Complement
  • Complement 5a
  • Complement Component 5a

Qualificatif(s) autorisé(s)

Action(s) pharmacologique(s)

Traductions

  • Complément C5a

    français

  • 80295-54-1
  • Complement C5a
  • Composant C5a du complément
  • Fraction C5a du complément
  • Fragment C5a du complément

URI

http://data.loterre.fr/ark:/67375/JVR-ZPZCDMQ7-J

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RDF/XML TURTLE JSON-LD Date de création 14/07/1989, dernière modification le 28/06/2016