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Concept information

Terme préférentiel

Kininogen, High-Molecular-Weight  

Type

  • mesh:Descriptor

Définition

  • A plasma protein, molecular weight of 110 kD, that normally exists in plasma in a 1:1 complex with PREKALLIKREIN. HMWK is split by plasma kallikrein to produce BRADYKININ. The complex is a cofactor in the activation of coagulation factor XII. The product of this reaction, XIIa, in turn activates prekallikrein to KALLIKREINS. (From Stedman, 26th ed)

Concept générique

Synonyme(s)

  • Fitzgerald Factor
  • High Molecular Weight Kininogen
  • High-Molecular-Weight Kininogen
  • High Molecular Weight Kininogens
  • High-Molecular-Weight Kininogens
  • HMWK
  • Kininogens, High Molecular Weight

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-ZTS1NGZN-D

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RDF/XML TURTLE JSON-LD Date de création 20/06/1997, dernière modification le 05/07/2006