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social science subjects > health and social care > global health > systemic diseases > Tay-Sachs disease
... > social science subjects > psychology > behavior mechanisms > human development > health and well-being > Tay-Sachs disease

Preferred term

Tay-Sachs disease  

Definition

  • Tay-Sachs disease (TSD), or GM2 gangliosidosis, is a fatal genetic lipid storage disorder where harmful quantities of the fatty substance ganglioside GM2 build up in tissues and nerve cells in the brain. This is from insufficient activity of the enzyme beta-hexosaminidase A which catalyzes (speeds up) the breakdown of acidic fatty materials or gangliosides. [Source: Encyclopedia of Global Health; Tay-Sachs Disease]

Broader concept

Belongs to group

URI

http://data.loterre.fr/ark:/67375/N9J-TS1RF5MG-X

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