: SAGE: point mutation

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point mutation

A point mutation or substitution in DNA research involves a mutation where the replacement of a single base nucleotide is made with another nucle-otide—nucleotides being the chemical compound that is found in the structural units of DNA. Essentially, the mutation involves the insertion or deletion of a single base pair, which can have, or may lead to, a more-than-adverse effect on any synthesized protein owing to the nucleotides being read in triple sequences. Three levels of mutation are involved. [Source: Encyclopedia of Global Health; Point Mutation]

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