Concept information
Preferred term
long-term potentiation
Definition
- Process resulting in long-lasting increase in synapse efficiency (a few hours to several weeks) after a series of high-frequency electrical stimulation.
Broader concept
Entry terms
- long-term synaptic potentiation
- LTP
Belongs to group
Bibliographic citation(s)
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• Bliss, T. V., & Lømo, T. (1973). Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path. The Journal of Physiology, 232(2), 331–356. https://doi.org/10.1113/jphysiol.1973.sp010274
[Study type: empirical study / Access: closed]
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• Lømo, T. (1966). Frequency potentiation of excitatory synaptic activity in the dentate area of the hippocampal formation. Acta Physiologica Scandinavica, 68 (Suppl 277), 128.
[Study type: empirical study / Access: closed]
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• Lømo, T. (2018). Discovering long‐term potentiation (LTP) – recollections and reflections on what came after. Acta Physiologica, 222(2), 1–1. https://doi.org/10.1111/apha.12921
[Study type: historical study, literature review / Access: closed]
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• Nicoll, R. A. (2017). A brief history of long-term potentiation. Neuron, 93(2), 281–290. https://doi.org/10.1016/j.neuron.2016.12.015
[Study type: historical study / Access: open]
Creator
- Frank Arnould
In other languages
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French
-
potentialisation synaptique à long terme
URI
http://data.loterre.fr/ark:/67375/P66-NG7QTM2N-0
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