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Concept information

Terme préférentiel

neurogenic hypthothesis  

Définition

  • The hypothesis proposed by Josselyn and Frankland (2012) to explain infantile amnesia. The hippocampus of infants (humans, non-human primates, and rodents) undergoes a high level of neurogenesis, resulting in the replacement of existing synaptic connections in hippocampal memory circuits (neural networks in the hippocampus that encode memories). Therefore, this high level of neurogenesis is accompanied by an inability to form stable long-term memories. When the level of neurogenesis decreases, the formation of long-term memories becomes possible.

Concept générique

Appartient au groupe

Référence(s) bibliographique(s)

  • • Guskjolen, A., Kenney, J. W., Parra, J. de la, Yeung, B. A., Josselyn, S. A., & Frankland, P. W. (2018). Recovery of “lost” infant memories in mice. Current Biology, 28(14), 2283-2290.e3. https://doi.org/10.1016/j.cub.2018.05.059

    [Study type: empirical study / Access: open]

  • • Josselyn, S. A., & Frankland, P. W. (2012). Infantile amnesia: A neurogenic hypothesis. Learning & Memory, 19(9), 423-433. https://doi.org/10.1101/lm.021311.110

    [Study type: literature review / Access: closed]

Créateur

  • Frank Arnould

Revu par

  • Antoine Bouyeure

Traductions

URI

http://data.loterre.fr/ark:/67375/P66-T41CSTSG-0

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RDF/XML TURTLE JSON-LD Date de création 04/12/2017, dernière modification le 22/03/2023